SN educated patient and caregiver about Lidocaine patches. After you are finished using a patch, remove it and dispose of it and keep it out of reach of children and pets. Lidocaine patches may cause side effects like burning or discomfort in the place you applied the patch, redness or swelling of the skin under the patch. If any of these symptoms occur, remove your patch and do not put it back on until the symptoms go away. Tell your doctor if any of these symptoms are severe or do not go away: