Instructed patient on new medication Sulindac. Sulindac may also be used for purposes not listed. Sulindac can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Even people without heart disease or risk factors could have a stroke or heart attack while taking this medicine. You should not use sulindac if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID. Patient verbalized understanding.