SN instructed patient / caregiver that the combination preparation fluticasone/salmeterol (Advair diskus) is a formulation containing fluticasone propionate and salmeterol xinafoate, used in the management of asthma and chronic obstructive pulmonary disease. Commun side effect / adverse reaction may include: Body aches or pain, choking, congestion, dryness of the throat, high-pitched noise when breathing, hoarseness, runny nose, sneezing, trouble with swallowing, voice changes. Less common side effect / adverse reaction: Cough-producing mucus, flu-like symptoms, irritation or inflammation of the eye, muscle pain, pain or tenderness around the eyes and cheekbones, sleep disorders, stuffy nose, white patches in the mouth or throat or on the tongue.